Moraga, CA, United States of America

John F Lyons

USPTO Granted Patents = 3 

Average Co-Inventor Count = 2.4

ph-index = 2

Forward Citations = 102(Granted Patents)


Company Filing History:


Years Active: 2005-2007

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3 patents (USPTO):Explore Patents

Title: John F Lyons: Pioneering the Fight Against Cancer Through Innovative Patents

Introduction

John F Lyons, an accomplished inventor based in Moraga, California, has made significant contributions to cancer research through his innovative patents. With a total of three patents, Lyons focuses on developing methods to treat various cancers, particularly those associated with the abnormal activity of kinases.

Latest Patents

One of Lyons' latest patents is centered on RAF-MEK-ERK pathway inhibitors to treat cancer. This invention details materials and methods aimed at addressing cancers that arise from the up-regulation of the RAF-MEK-ERK pathway. Specifically, it targets chronic myelogenous leukemia, especially in cases where the cancer exhibits resistance to the inhibition of the Bcr-Abl tyrosine kinase, imatinib.

Another significant patent, titled "Method for treating diseases associated with abnormal kinase activity," provides methods for treating conditions linked to abnormal kinase activity. This method involves the administration of a DNA methylation inhibitor and a kinase inhibitor in therapeutically effective amounts. Lyons’ innovation is particularly relevant for cancers associated with the abnormal activities of kinases, including phosphatidylinositol 3'-kinase (PI3K) and various receptor families such as EGFR, PDGFR, and VEGFR.

Career Highlights

Lyons has garnered extensive experience working with prominent companies in the pharmaceutical sector. He has been affiliated with Supergen, Inc. and Onyx Pharmaceuticals, Inc., where he collaborated on groundbreaking cancer therapies. His work in these organizations has undoubtedly enriched his research and development skills.

Collaborations

Throughout his career, Lyons has collaborated with notable figures in the industry. Among his coworkers are Joseph Rubinfeld and Gideon Bollag, both of whom have played crucial roles in advancing cancer treatment methodologies. These collaborations have fostered a creative environment that encourages innovative solutions to complex medical challenges.

Conclusion

John F Lyons exemplifies the spirit of innovation in cancer research through his patents and collaborations. His work in developing treatments for cancers associated with abnormal kinase activity showcases the potential of scientific advancements in improving patient health outcomes. As research continues to evolve, Lyons stands as a key figure in the ongoing battle against cancer.

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