The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2007

Filed:

Dec. 03, 2002
Applicants:

John F. Lyons, Moraga, CA (US);

Gideon Bollag, Hercules, CA (US);

Inventors:

John F. Lyons, Moraga, CA (US);

Gideon Bollag, Hercules, CA (US);

Assignee:

Onyx Pharmaceuticals, Inc, Emeryville, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/025 (2006.01); A61K 31/03 (2006.01); A61K 31/13 (2006.01); A61K 31/075 (2006.01); A61K 31/08 (2006.01); A61K 31/17 (2006.01); A61K 31/33 (2006.01);
U.S. Cl.
CPC ...
Abstract

Materials and methods for treating certain cancers are described, preferably cancers that result from the up-regulation of the RAF-MEK-ERK pathway, and more preferably chronic myelogenous leukemia, and which cancer is preferably resistant to the inhibition of the Bcr-Abl tyrosine kinase, imatinib.


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