Location History:
- Fort Wayne, IN (US) (1976 - 1981)
- North Palm Beach, FL (US) (1980 - 1985)
- Hershey, PA (US) (2014)
- Mechanicsburg, PA (US) (2014)
Company Filing History:
1 out of 8 
6 out of 832,680 Years Active: 1976-2014
Title: Innovations and Contributions of John F Harms
Introduction
John F Harms is a notable inventor based in Fort Wayne, IN (US). He has made significant contributions to the field of cancer treatment, particularly focusing on pancreatic cancer. With a total of 7 patents to his name, his work has the potential to impact the lives of many patients.
Latest Patents
One of his latest patents involves a composition and method for the treatment of gastrin-mediated cancers. This innovative approach utilizes gastrin mRNA down-regulation through stable transfection of an antisense gastrin cDNA or shRNA constructs. The research indicates a significant reduction in the growth of human pancreatic cancer. The tumor growth rate and incidence of metastases in both wild-type and transfected pancreatic cancer cells are directly proportional to the levels of gastrin mRNA expression. To enhance the delivery of siRNA to tumors, nanoliposomes can be loaded with gastrin siRNA, achieving a significant reduction of tumors in mice. Additionally, he has identified and characterized a specific CCK-C receptor antibody for human pancreatic cancer, which may aid in early detection and staging of the disease.
Career Highlights
Throughout his career, John F Harms has worked with various companies, including Harmsco, Inc. His innovative research and patents reflect his dedication to advancing medical science and improving treatment options for cancer patients.
Collaborations
John has collaborated with notable coworkers such as Jill P Smith and Gail L Matters, contributing to the collective knowledge and advancements in cancer research.
Conclusion
John F Harms is a distinguished inventor whose work in cancer treatment showcases his commitment to innovation and improving patient outcomes. His contributions are invaluable in the ongoing fight against pancreatic cancer.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.