Company Filing History:
Years Active: 1995-2002
Title: The Innovative Contributions of John E. Skonier
Introduction
John E. Skonier, an accomplished inventor based in Seattle, WA, has made significant contributions to biomedical research through his innovative patents. With a total of two patents to his name, Skonier has focused on advancing medical science, particularly in the areas of antibodies and gene therapy.
Latest Patents
One of his latest patents involves monoclonal antibodies to human CD6. This invention provides antibodies and other binding agents that specifically target the SRCR domains of human CD6 (hCD6), offering advantageous properties such as the ability to substantially inhibit the binding of activated leukocyte adhesion molecule (ALCAM) to hCD6. These binding agents serve crucial roles in screening peptides and drugs that may also interact with hCD6 and modulate ALCAM binding, making them valuable for diagnostic and therapeutic approaches in managing inflammatory and autoimmune diseases.
His second patent centers around a TGF-β induced gene and protein, referred to as BIG-H3. This innovative discovery describes a novel gene that encodes a 683 amino acid protein, characterized by four homologous repeat regions. Induced in mammalian and specifically human cells upon treatment with TGF-β, this gene has shown the capacity to inhibit the growth of tumor cells, heralding potential advancements in cancer treatment.
Career Highlights
John E. Skonier is currently associated with Bristol-Myers Squibb Company, where he continues to leverage his expertise in developing groundbreaking therapies for various diseases. His work has paved the way for therapeutic breakthroughs, affirming his status as a significant contributor to the field of biomedical innovation.
Collaborations
Throughout his career, Skonier has collaborated with esteemed colleagues, including Anthony F. Purchio and Michael G. Neubauer. These collaborations have enabled him to enhance the scope and impact of his research, thereby contributing to the overall advancement of medical science.
Conclusion
John E. Skonier's innovative work and significant patents highlight his contributions to biomedical research. As an inventor, his focus on therapeutic applications in both autoimmune disorders and cancer treatment showcases the practical implications of his discoveries. His ongoing work at Bristol-Myers Squibb Company, along with his collaborations, promises to yield further advancements in the field.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.