The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2002
Filed:
Feb. 25, 1998
Gary C. Starling, Lawrenceville, NJ (US);
Anthony W. Siadak, Seattle, WA (US);
Michael A. Bowen, Princeton, NJ (US);
Alejandro A. Aruffo, Belle Mead, NJ (US);
Jurgen Bajorath, Lynnwood, WA (US);
Dale L. Bodian, Paoli, PA (US);
John E. Skonier, Seattle, WA (US);
Bristol-Myers Squibb Company, New York, NY (US);
Abstract
The invention provides antibodies and other binding agents that bind specifically to SRCR domains of human CD6 (hCD6) and have advantageous properties, including the capacity to substantially inhibit binding of activated leukocyte adhesion molecule (ALCAM) to hCD6. The binding agents of the invention are useful, inter alia, in methods for screening peptides and drugs that also bind to hCD6 and/or modulate ALCAM binding to hCD6, as well as in diagnostic and therapeutic methods for management and treatment of inflammatory and autoimmune diseases.