Company Filing History:
Years Active: 1999-2008
Title: Innovations of John E Cabaj
Introduction
John E Cabaj is a notable inventor based in Sheboygan, WI (US). He has made significant contributions to the field of chemistry, particularly in the preparation of various chemical compounds. With a total of 2 patents to his name, Cabaj's work has implications in pharmaceuticals and medicinal chemistry.
Latest Patents
Cabaj's latest patents include the "Preparation of amides of retinoic acid via mixed anhydride and mixed carbonate intermediates." This patent discloses processes for preparing amides of retinoic acid, along with intermediates useful in their preparation. One version of the invention involves the production of fenretinide through the activation of retinoic acid (tretinoin) using a mixed anhydride or mixed carbonate, followed by a reaction with 4-aminophenol. Additionally, other amides and isomers of retinoic acid, such as the 9-cis-form or 13-cis-form, can also be synthesized using this method. Another significant patent is the "Process to prepare tolterodine," which introduces a novel intermediate, 3,4-dihydro-6-methyl-4-phenyl-2H-benzopyran-2-ol, and an improved process for the preparation of tolterodine.
Career Highlights
Throughout his career, John E Cabaj has worked with prominent companies in the pharmaceutical industry, including Pharmacia & Upjohn Company and Cedarburg Pharmaceuticals, Inc. His experience in these organizations has contributed to his expertise in chemical processes and innovations.
Collaborations
Cabaj has collaborated with notable coworkers such as James R Gage and Jeff Hutchison. Their combined efforts have likely enhanced the development and refinement of the innovative processes that Cabaj has patented.
Conclusion
John E Cabaj's contributions to the field of chemistry through his patents and collaborations highlight his role as an influential inventor. His work continues to impact the pharmaceutical industry and advance the understanding of chemical processes.