Location History:
- New York, NY (US) (2020)
- Forest Hills, NY (US) (2021)
Company Filing History:
2 out of 270 
1 out of 548 
Years Active: 2020-2021
Title: John Cijiang He: Innovator in Kidney Disease Research
Introduction
John Cijiang He is a prominent inventor based in New York, NY (US). He has made significant contributions to the field of kidney disease research, holding 2 patents that focus on innovative methods for diagnosing and treating chronic kidney conditions.
Latest Patents
His latest patents include a method for identifying the risk of developing Chronic Allograft Nephropathy (CAN) in patients who have received kidney transplants. This method involves identifying the race of the donor, determining the levels of SHROOM 3 expression in a kidney biopsy specimen obtained from the patient, and comparing these levels with a control. If the SHROOM 3 expression is significantly higher in the allograft than in the control, the patient is diagnosed as being at risk for CAN. Another notable patent involves oxadiazole inhibitors of HIPK2 for treating kidney fibrosis. These compounds selectively inhibit Smad3 activation and are useful in treating fibrotic diseases, particularly renal fibrosis.
Career Highlights
John Cijiang He has worked at prestigious institutions such as the Icahn School of Medicine at Mount Sinai and the University of Kansas Medical Center Research Institute. His work has been instrumental in advancing the understanding and treatment of kidney-related diseases.
Collaborations
He has collaborated with notable colleagues, including Barbara Murphy and Ruijie Liu, contributing to a rich environment of research and innovation.
Conclusion
John Cijiang He is a key figure in kidney disease research, with innovative patents that have the potential to improve patient outcomes. His work continues to influence the field and inspire future research endeavors.