The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2026
Filed:
Feb. 09, 2022
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
The United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);
Richard T. Beresis, San Francisco, CA (US);
John Cijiang He, Forest Hills, NY (US);
Kyung Lee, Bronx, NY (US);
Icahn School of Medicine at Mount Sinai, New York, NY (US);
The United States Government as Represented by the Department of Veterans Affairs, Washington, DC (US);
Abstract
Compounds that are selective inhibitors of Smad3 activation are disclosed. The compounds are (3-aryl-1,2,4-oxadiazol-5-yl)-3,4-dihydro-2H-pyrano[2,3-b]pyridines of the following structure: in which Ar is aryl or heteroaryl. The compounds disclosed are useful in treatment of fibrotic disease, particularly renal fibrosis, and similar diseases associated with the dysregulation of the HIPK2/Smad3 signaling pathway.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile