John C Price

Title: John C Price: Innovator in Protein Measurement Technology

Introduction

John C Price is a notable inventor based in Hayward, California. He has made significant contributions to the field of protein measurement through his innovative patent. His work focuses on isotopic labeling techniques that enhance the understanding of protein levels and turnover in living organisms.

Latest Patents

John C Price holds a patent titled "Isotopic labeling for the measurement of global protein levels and turnover in vivo." This patent describes a method where a complete set of isotopically labeled amino acids is introduced into the diet of a test subject. The methodology ensures that a substantial percentage of these labeled amino acids is incorporated into newly synthesized proteins. Tissue samples are then collected at various time points, allowing for the extraction and separation of proteins. This enables individual analysis of different proteins across various tissues, determining their amount and isotopic labeling patterns. The technique can be further enhanced by combining it with proteolytic digestion and mass spectrometry to measure protein turnover rates for thousands of proteins.

Career Highlights

John C Price is affiliated with the University of California, where he continues to advance research in protein measurement technologies. His innovative approach has opened new avenues for understanding protein dynamics in biological systems.

Collaborations

Some of his notable coworkers include Stanley B Prusiner and Sina Ghaemmaghami, who have also contributed to advancements in the field of protein research.

Conclusion

John C Price's work in isotopic labeling represents a significant advancement in the measurement of protein levels and turnover in vivo. His contributions are vital for ongoing research in protein dynamics and have the potential to impact various scientific fields.