Johannes Backs

Title: Innovations by Inventor Johannes Backs

Introduction

Johannes Backs is a notable inventor based in Dallas, TX (US). He has made significant contributions to the field of medical treatments, particularly in relation to cardiac conditions. His innovative work focuses on the interaction between CaMKII and HDACs, which has implications for heart disease therapies.

Latest Patents

Johannes Backs holds a patent titled "Methods of treatment and uses for CaMKII and its interaction with HDACs and calpain." This invention provides methods for treating cardiac hypertrophy, heart failure, dilated cardiomyopathy, or hypertension through the use of CaMKII-HDAC binding domains. The patent reveals that CaMKII binds to HDAC4 at a specific site, which may lead to the dimerization of HDAC4 with other HDACs. This process can result in the export of HDACs from the nucleus to the cytoplasm, a significant event associated with the development of heart disease. The methods outlined in this patent represent novel approaches to prevent, treat, or identify therapies for various cardiac conditions.

Career Highlights

Throughout his career, Johannes Backs has worked with esteemed organizations such as the University of Texas System and Gilead Sciences, Inc. His experience in these institutions has contributed to his expertise in the field of cardiac research and treatment.

Collaborations

Johannes has collaborated with notable colleagues, including Brooke Harrison and Khai Huynh. These partnerships have likely enhanced his research and development efforts in the medical field.

Conclusion

Johannes Backs is a distinguished inventor whose work has the potential to significantly impact the treatment of heart diseases. His innovative patent and collaborations reflect his commitment to advancing medical science.