Location History:
- San Diego, CA (US) (2012 - 2017)
- Toronto, CA (2019 - 2023)
Company Filing History:
10 out of 410 
3 out of 31 
1 out of 541 
Years Active: 2012-2023
Title: Innovations of Johan Fransson
Introduction
Johan Fransson is a notable inventor based in Toronto, Canada, recognized for his significant contributions to the field of biotechnology. With a total of 15 patents to his name, he has made remarkable advancements in the development of therapeutic antibodies.
Latest Patents
Fransson's latest patents include the invention of neutralizing human anti-CD27 antibodies. These human antibodies are designed to block the binding of CD27 to its ligand CD70, effectively neutralizing the bioactivity of CD27. This includes inhibiting CD27 intracellular signaling, T-cell proliferation and activation, B-cell proliferation and differentiation, and alleviating antibody responses. Additionally, these antibodies can stimulate tumor cells by CD70 and promote the production of soluble mediators from T and B-cells. They hold potential for diagnosing or treating diseases associated with CD27 activity. Another significant patent involves nucleic acids encoding anti-CD154 antibodies. This invention relates to antagonistic antibodies that specifically bind to CD154, along with polynucleotides encoding these antibodies or their fragments, and methods for their production and use.
Career Highlights
Throughout his career, Johan Fransson has worked with prominent companies in the biotechnology sector, including Janssen Biotech, Inc. and Centocor Ortho Biotech Inc. His work has significantly impacted the development of therapeutic solutions in immunology.
Collaborations
Fransson has collaborated with esteemed colleagues such as Alexey Teplyakov and Juan C Almagro, contributing to the advancement of innovative biotechnological solutions.
Conclusion
Johan Fransson's contributions to biotechnology through his patents and collaborations highlight his role as a leading inventor in the field. His work continues to influence the development of therapeutic antibodies and their applications in medicine.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.