Pikesville, MD, United States of America

Joel Chaim Sunshine

USPTO Granted Patents = 6 

Average Co-Inventor Count = 5.1

ph-index = 2

Forward Citations = 7(Granted Patents)


Location History:

  • Pikesville, MD (US) (2017 - 2020)
  • Baltimore, MD (US) (2015 - 2024)

Company Filing History:


Years Active: 2015-2024

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6 patents (USPTO):Explore Patents

Title: Innovations by Joel Chaim Sunshine

Introduction

Joel Chaim Sunshine is a notable inventor based in Pikesville, MD (US). He has made significant contributions to the field of polymer science, particularly in the development of materials for gene delivery and therapeutic applications. With a total of 6 patents, his work has the potential to impact cancer therapeutics and regenerative medicine.

Latest Patents

One of his latest patents involves the creation of multicomponent degradable cationic polymers. These degradable polymers are synthesized to self-assemble with DNA, forming particles that are effective for gene delivery. Notably, small changes in polymer synthesis conditions, particle formulation conditions, and polymer structure can lead to significant changes in efficacy, which varies depending on the cell type. The polymers developed by Sunshine have shown to be more effective than commercially available materials, such as LIPOFECTAMINE 2000™, FUGENE®, or polyethylenimine (PEI), particularly for gene delivery to cancerous fibroblasts or human primary fibroblasts. This innovation may prove useful in cancer therapeutics and regenerative medicine.

Another significant patent focuses on peptide/particle delivery systems. This invention includes polymeric nanoparticles, microparticles, and gels designed for delivering therapeutic agents, such as peptides, to target cells. The disclosed methods aim to treat diseases, including angiogenesis-dependent conditions like age-related macular degeneration and cancer. The formulation, stabilization, and administration of single peptides or combinations of peptides via these polymeric particle and gel delivery systems are also covered in this patent.

Career Highlights

Joel Chaim Sunshine is affiliated with The Johns Hopkins University, where he continues to advance his research in polymer science and its applications in medicine. His work is characterized by a commitment to innovation and the development of effective therapeutic solutions.

Collaborations

Sunshine has collaborated with notable colleagues, including Jordan J Green and Ron B Shmueli, contributing to the advancement of research in his field.

Conclusion

Joel Chaim Sunshine's innovative work in polymer science and gene delivery systems showcases his dedication to improving therapeutic options for patients. His contributions are paving the way for future advancements in cancer treatment and regenerative medicine.

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