The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2020

Filed:

Jul. 10, 2017
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Jordan Jamieson Green, Nottingham, MD (US);

Aleksander S. Popel, Lutherville, MD (US);

Joel Chaim Sunshine, Pikesville, MD (US);

Ron B. Shmueli, Baltimore, MD (US);

Stephany Yi Tzeng, Baltimore, MD (US);

Kristen Lynn Kozielski, Baltimore, MD (US);

Assignee:

THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 9/19 (2006.01); A61K 9/51 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); A61K 31/713 (2006.01); A61K 38/39 (2006.01); A61K 47/34 (2017.01); B82Y 5/00 (2011.01); C12N 15/88 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5026 (2013.01); A61K 9/0019 (2013.01); A61K 9/06 (2013.01); A61K 9/19 (2013.01); A61K 9/5146 (2013.01); A61K 31/711 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 38/39 (2013.01); A61K 47/34 (2013.01); B82Y 5/00 (2013.01); C12N 15/111 (2013.01); C12N 15/88 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); Y10T 428/2982 (2015.01);
Abstract

Polymeric nanoparticles, microparticles, and gels for delivering cargo, e.g., a therapeutic agent, such as a peptide, to a target, e.g., a cell, and their use for treating diseases, including angiogenesis-dependent diseases, such as age-related macular degeneration and cancer, are disclosed. Methods for formulating, stabilizing, and administering single peptides or combinations of peptides via polymeric particle and gel delivery systems also are disclosed.


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