Joanne T Douglas

Title: Celebrating the Innovations of Inventor Joanne T. Douglas

Introduction

Joanne T. Douglas, based in Huntsville, Alabama, is a distinguished inventor with a notable expertise in the field of gene therapy. With two patents to her name, she has made significant contributions to the advancement of viral vector technology aimed at enhancing the efficacy of gene delivery systems.

Latest Patents

Joanne T. Douglas's latest patents include two innovative inventions. The first, titled "Fiber receptor-independent system for the propagation of adenoviral vectors," introduces a genetic method for the manipulation of the fiber protein of adenovirus. By employing a C-terminal tag, this invention enables the propagation of adenovirus in a cell line that has been transfected with a sequence encoding an artificial receptor. This groundbreaking work enhances the potential for therapeutic applications.

The second patent, "Viral vectors with modified tropism," focuses on gene therapy and encompasses various therapeutic agents and compositions. This invention details systems and methods that employ virus-antibody-ligand conjugates to target and deliver non-native nucleotide sequences specifically to designated cells, further expanding the possibilities for targeted gene therapy.

Career Highlights

Throughout her career, Joanne T. Douglas has had the privilege to work with several esteemed organizations, including the UAB Research Foundation. Her experience at these institutions has facilitated her research endeavors and has played a significant role in her contributions to the scientific community.

Collaborations

Joanne has collaborated with many talented professionals in her field, including notable coworkers such as David T. Curiel and Barbara A. Sosnowski. These partnerships have enriched her work and led to advancements in the applications of her patents.

Conclusion

Joanne T. Douglas continues to be an influential figure in the realm of innovations related to gene therapy. Her inventive spirit and commitment to research not only enhance our understanding of viral vectors but also pave the way for future advancements in medical therapies. Her contributions reflect the importance of dedicated researchers in the ongoing quest to address challenges in health and medicine.