Jingxiao Ji

Title: Innovations of Jingxiao Ji in Dibasic Organic Acid Production

Introduction

Jingxiao Ji is a notable inventor based in Tianjin, China, recognized for his contributions to the field of biotechnology. He has been instrumental in developing engineered strains for synthesizing dibasic organic acids, which are essential in various industrial applications. With a total of two patents to his name, Ji's work exemplifies the intersection of innovation and practical application in science.

Latest Patents

Jingxiao Ji's latest patents focus on the development of a dibasic organic acid producing strain and its preparation and application. The engineered strain he has developed introduces or up-regulates the expression of a positive regulator gene for the synthesis of dibasic organic acids. Additionally, it down-regulates the expression of a negative regulator gene, significantly improving the strain's capability to produce these acids. The dibasic organic acids produced include malic acid, succinic acid, fumaric acid, oxaloacetic acid, glutaric acid, and adipic acid. The positive regulator gene expression products include aspartate aminotransferase, glutamic acid-aspartate transporter, C4-dicarboxylic acid transporter, pyruvate carboxylase, malate dehydrogenase, and glucose transporter. Conversely, the negative regulatory gene expression products include succinyl-CoA synthase and malic acid-alpha ketoglutarate transporter.

Career Highlights

Jingxiao Ji is affiliated with the Chinese Academy of Sciences, where he conducts his research and development activities. His work has significantly advanced the understanding and production of dibasic organic acids, contributing to both academic knowledge and industrial practices.

Collaborations

Throughout his career, Ji has collaborated with esteemed colleagues, including Chaoguang Tian and Jingen Li. These collaborations have fostered a productive research environment, leading to innovative solutions in biotechnology.

Conclusion

Jingxiao Ji's contributions to the field of dibasic organic acid production highlight the importance of innovation in biotechnology. His patents and research efforts continue to influence the industry and pave the way for future advancements.