Jihae Sohn

Title: Innovations and Contributions of Jihae Sohn in Plasma Protein Stabilization

Introduction

Jihae Sohn is an accomplished inventor based in Brighton, MA, known for his significant contributions to the field of plasma products. With a total of seven patents to his name, he has been instrumental in developing innovative methods and formulations that enhance the stability and efficacy of plasma proteins.

Latest Patents

Among his recent patents, Jihae Sohn has developed a groundbreaking blood plasma product. This invention is characterized by its unique spray-dried plasma composition, which exhibits several remarkable properties. When reconstituted, the plasma is largely amorphous, contains reduced large particulates, and has low residual moisture. Moreover, it reconstitutes rapidly in under four minutes and maintains high stability under various storage conditions, including refrigeration and elevated temperatures. Notably, this innovative plasma formulation allows for the recovery of fragile proteins, such as von Willebrand's factor, while achieving a near-normal pH level without the need for additional pH adjustments. Furthermore, it demonstrates reduced complement activation, enhancing its therapeutic potential.

Another significant patent by Jihae Sohn focuses on formulations and methods for the contemporaneous stabilization of active proteins during spray drying and storage. This method involves treating plasma with a physiologically compatible spray-dry stable acidic substance (SDSAS), which not only improves the recovery of plasma proteins but also ensures their long-term stability. This advancement offers promising solutions for the preservation of vital plasma components, which could have substantial implications in medical applications.

Career Highlights

Jihae Sohn is a key member of Velico Medical, Inc., where he has utilized his expertise to push the boundaries of plasma product innovation. His dedication to research and development has resulted in a series of patents that contribute to the advancement of medical technology, particularly in the fields of hemotherapy and protein stabilization.

Collaborations

In his professional journey, Jihae has collaborated with talented colleagues, including Qiyong Peter Liu and Rud Karly Lucien. These collaborations underscore the importance of teamwork and knowledge sharing in driving innovation within the medical sector.

Conclusion

Overall, Jihae Sohn's inventive contributions stand at the forefront of plasma protein stabilization. Through his patents and collaborative efforts, he has made a significant impact on the medical industry, promising advancements that could potentially improve patient outcomes and ensure the viability of critical plasma products.