The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2024
Filed:
Sep. 15, 2022
Velico Medical, Inc., Beverly, MA (US);
Qiyong Peter Liu, Newton, MA (US);
Herman E. Snyder, W. Lafayette, IN (US);
Kyle D. Erickson, Melrose, MA (US);
Evan P. Ordway, Salem, MA (US);
William J. Merritt, Danvers, MA (US);
Richard Meehan, Caragh County, IE;
Robert R. Andrews, Norfolk, MA (US);
Clair Strohl, Emmaus, PA (US);
Jihae Sohn, Salem, MA (US);
Mark A. Popovsky, Sharon, MA (US);
Lisa A. Buckley, Portland, OR (US);
Velico Medical, Inc., Beverly, MA (US);
Abstract
The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in COor other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A).