Lisa A Buckley

Title: Innovations by Lisa A. Buckley

Introduction

Lisa A. Buckley is a prominent inventor based in Portland, Oregon. She has made significant contributions to the field of medical technology, particularly in the area of plasma processing. With a total of six patents to her name, her work has the potential to impact various medical applications.

Latest Patents

One of her latest patents is a method for providing dried plasma. This invention includes a spray drying disposable device designed for use in a spray drying system. The device features a spray drying head and a plasma drying chamber. The head is equipped with a spray dry nozzle assembly that is in fluid communication with both the plasma source and a pressurized aerosol gas source. The pressurized gas flows in a vortex pattern, atomizing plasma droplets within the chamber. Additionally, the head contains a plenum that maintains uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum, featuring drying gas jets that supply the drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets, resulting in dried plasma particles and humid air. A capture filter is included to capture the dried plasma particles while allowing the humid air to pass through the gas outlet and exhaust port.

Another notable patent relates to a spray dried plasma composition. This composition has several key characteristics, including being largely amorphous and free of cholesterol crystals when reconstituted. It also reduces the number of large particulates, has low residual moisture, and reconstitutes rapidly in under four minutes. The plasma composition is highly stable when stored under various conditions, including refrigeration and room temperature. It allows for longer storage periods and exhibits recovery of fragile proteins, such as von Willebrand's factor. When reconstituted with Sterile Water for Injection (SWFI), the plasma maintains a near-normal pH without requiring treatment or storage in CO or other pH adjustments. Furthermore, it shows reduced complement activation.

Career Highlights

Throughout her career, Lisa has worked with notable organizations, including Velico Medical, Inc. and Sisters of Providence in Oregon. Her innovative work in these companies has contributed to advancements in medical technology and plasma processing.

Collaborations

Lisa has collaborated with several professionals in her field, including Herman E. Snyder and Evan P. Ordway. These collaborations have further enhanced her research and development efforts.