Company Filing History:
Years Active: 2019-2023
Title: Jie Li: Innovator in Anticancer Research
Introduction
Jie Li is a prominent inventor based in San Diego, CA, known for his contributions to the field of medicinal chemistry and cancer research. With a total of 3 patents, he has made significant strides in developing innovative compounds and methods aimed at combating cancer.
Latest Patents
One of Jie Li's latest patents focuses on arylfluorosulfate compounds and methods. This patent describes a high-throughput screening method for identifying candidate anticancer medicinal agents derived from phenolic compounds. The method involves the in situ generation of arylfluorosulfate compounds in multi-well plates through the reaction of phenolic compounds in DMSO with a saturated solution of SOF dissolved in a solvent such as acetonitrile, in the presence of an organic base. The generated fluoride ion then reacts with trimethylsilanol to form volatile trimethylsilyl fluoride. The solvents, organic base, and silyl compounds are subsequently removed in vacuo, yielding arylfluorosulfate compounds suitable for biological screening in cancer cell lines without further purification.
Another significant patent involves engineered cells that comprise a chemical or biological moiety covalently bound to a cell surface glycan. This moiety can be a small molecule, polynucleotide, polypeptide, or antibody. The patent also includes compositions comprising these engineered cells and methods for making and using them.
Career Highlights
Jie Li has worked with esteemed organizations such as The Scripps Research Institute and Novartis AG. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Some of Jie Li's notable coworkers include Peng Wu and Yiran Zhou. Their collaborative efforts have further advanced the research and development of innovative solutions in cancer treatment.
Conclusion
Jie Li's work exemplifies the intersection of innovation and healthcare, particularly in the fight against cancer. His patents and research contributions continue to pave the way for new therapeutic approaches.