Company Filing History:
Years Active: 2019-2020
Title: Innovations of Jiansheng Han in Pharmaceutical Chemistry
Introduction
Jiansheng Han is a notable inventor based in Shanghai, China. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of novel compounds with improved properties. With a total of two patents to his name, Han's work focuses on enhancing the efficacy and stability of pharmaceutical formulations.
Latest Patents
Jiansheng Han's latest patents include innovative compounds that demonstrate improved solubility and stability. The first patent is for a salt of a quinazoline derivative, specifically N-[4-(3-chlorine-4-fluoroanilino)]-7-(3-morpholinepropanol)-6-(2-fluoroacrylamide)-quinazoline. This compound exhibits enhanced water solubility compared to known quinazoline derivatives, with specific salts such as citrate, benzene sulfonate, and ethanedisulphonate showing better crystallinity and moisture resistance.
The second patent involves salts of a morpholine derivative, which includes various crystal forms and processes for their production. These salts, such as malate, tartrate, hydrochloride, acetate, and naphthalene disulfonate, offer improved crystalline states, water solubility, light stability, and thermal stability compared to the free base of the morpholine derivative. The invention also outlines preparation methods and pharmaceutical compositions that utilize these novel salts.
Career Highlights
Jiansheng Han is currently associated with Shanghai Pharmaceuticals Holding Co., Ltd., where he continues to innovate in the pharmaceutical sector. His work is characterized by a commitment to developing compounds that address critical challenges in drug formulation and delivery.
Collaborations
Han collaborates with esteemed colleagues, including Guangxin Xia and Di Li, to further advance research and development in pharmaceutical sciences. Their combined expertise contributes to the successful realization of innovative solutions in the industry.
Conclusion
Jiansheng Han's contributions to pharmaceutical chemistry through his patents reflect his dedication to improving drug formulations. His innovative work continues to pave the way for advancements in the field, showcasing the importance of research and collaboration in developing effective pharmaceutical solutions.