Jianming Lu

Title: The Innovative Contributions of Jianming Lu

Introduction

Jianming Lu is a notable inventor based in Potomac, MD (US), recognized for his significant contributions to the field of biotechnology. With 2 patents to his name, he has made strides in developing advanced methodologies for cell-based assays.

Latest Patents

One of Jianming Lu's latest patents focuses on cell-based assays employing voltage and calcium dyes. This patent discloses novel compositions and methods that utilize cyclic nucleotide-gated channels and fluorescence dyes to detect changes in intracellular cAMP levels. These changes often occur in response to the stimulation of G-protein-coupled receptors. The patent also highlights the use of CNG mutants with pore mutations that enhance sensitivity to cAMP while decreasing divalent cation-mediated blockage. This innovation is applicable in various assays, including the detection of G-protein-coupled receptor activity. Additionally, the patent introduces novel dye quencher formulations that are particularly suited for cell-based assays of protein interactions.

Career Highlights

Jianming Lu is currently associated with Atto Bioscience Inc., where he continues to push the boundaries of scientific research and innovation. His work has been instrumental in advancing the understanding of cellular mechanisms and their applications in therapeutic contexts.

Collaborations

Throughout his career, Jianming Lu has collaborated with esteemed colleagues, including Yong Yao and Liang Cao. These partnerships have fostered a collaborative environment that enhances the quality and impact of their research.

Conclusion

Jianming Lu's innovative work in biotechnology, particularly in the development of cell-based assays, showcases his commitment to advancing scientific knowledge. His contributions are paving the way for future discoveries in the field.