Company Filing History:
Years Active: 2025
Title: Innovations of Jianmin Li in Transthyretin Detection
Introduction
Jianmin Li is an accomplished inventor based in Castro Valley, California. He has made significant contributions to the field of medical diagnostics, particularly in the detection of transthyretin (TTR). His innovative methods have the potential to improve the diagnosis and monitoring of diseases associated with TTR accumulation.
Latest Patents
Jianmin Li holds a patent for "Methods of detecting transthyretin." This invention provides methods for detecting TTR using a capture antibody and a reporter antibody. The capture antibody preferentially binds to misfolded TTR over the native tetrameric form of TTR. Specifically, it binds to an epitope within amino acid residues 89-97 or 101-109 of TTR. Examples of suitable capture antibodies include 9D5 and 18C5. These methods can be utilized for diagnosing diseases related to TTR accumulation, such as TTR amyloidosis, and for monitoring the efficacy of TTR therapies.
Career Highlights
Jianmin Li is currently employed at Novo Nordisk A/S, where he continues to advance his research in the field of diagnostics. His work is instrumental in developing innovative solutions that address critical health issues.
Collaborations
Jianmin has collaborated with notable colleagues, including Joshua Reginald Salmans and Svetlana Alexander. Their combined expertise contributes to the success of their projects and enhances the impact of their research.
Conclusion
Jianmin Li's contributions to the detection of transthyretin represent a significant advancement in medical diagnostics. His innovative methods have the potential to improve patient outcomes and enhance the understanding of TTR-related diseases.