Location History:
- Hockessin, DE (US) (2000 - 2001)
- Wilmington, DE (US) (2001)
Company Filing History:
Years Active: 2000-2001
Title: **Jianguo Yin: Innovator in Pharmacology and Chemical Synthesis**
Introduction
Jianguo Yin, based in Hockessin, Delaware, is a prolific inventor with a commendable portfolio of six patents. His groundbreaking work primarily focuses on pharmaceutical compositions and methods that contribute significantly to medical science, particularly in battling diseases related to platelet aggregation and HIV.
Latest Patents
Among his latest innovations, Yin has developed a patent for Crystalline Roxifiban, a potent platelet glycoprotein IIb/IIIa antagonist. This invention presents roxifiban in crystalline form, characterized by two polymorphic variants, Form 1 and Form 2. The differentiation is rigorously established through x-ray powder diffraction and solid-state carbon NMR technologies. This pharmaceutical composition has significant implications for developing treatments aimed at diseases that stem from platelet aggregation.
Additionally, Jianguo Yin is credited with a novel Process for the Preparation of Cyclopropylacetylene. This synthesis method proves vital for the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one, known for its effectiveness as a human immunodeficiency virus (HIV) reverse transcriptase inhibitor. The process involves a systematic chemical reaction that utilizes readily available starting materials, thus enhancing industrial scalability and overall yield.
Career Highlights
Jianguo Yin has had a notable career at DuPont Pharmaceuticals Company and DuPont Pharmaceuticals, Inc., where he honed his skills and contributed to key developments in pharmaceutical research. His extensive experience at these renowned companies has played a pivotal role in shaping his inventive prowess.
Collaborations
Throughout his career, Yin has collaborated with esteemed colleagues, including Joseph M Fortunak and Jaan A Pesti. These partnerships have facilitated innovative approaches in his research and fostered a dynamic environment for scientific progress.
Conclusion
Jianguo Yin’s contributions to the fields of pharmacology and chemical synthesis underscore his role as a significant innovator. His patented inventions not only advance medical science but also stand to improve patient care, demonstrating the real-world impact of his work on global health challenges.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.