The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2001

Filed:

Jun. 15, 1998
Applicant:
Inventors:

Michael Blaise Maurin, Wilmington, DE (US);

Philip Ma, Chadds Ford, PA (US);

David John Meloni, Newark, DE (US);

Jaan A. Pesti, Wilmington, DE (US);

Lucius Thomas Rossano, Newark, DE (US);

Randall K. Ward, Wilmington, DE (US);

Jianguo Yin, Hockessin, DE (US);

Lin Hua Zhang, New Fairfield, CT (US);

Goss S. Kauffman, Bear, DE (US);

Assignee:

DuPont Pharmaceuticals Company, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/112 ; C07D / ; A61P 7/02 ;
U.S. Cl.
CPC ...
A61K 3/112 ; C07D / ; A61P 7/02 ;
Abstract

The potent platelet glycoprotein IIb/IIIa antagonist, roxifiban, is produced in crystalline form. Crystalline roxifiban exists in two polymorphic forms, designated Form 1 and Form 2. These polymorphic forms are characterized by x-ray powder diffraction and solid-state carbon NMR. Pharmaceutical compositions and methods for the treatment or prevention of diseases mediated by platelet aggregation are described.


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