Jian-Shen Qi

Title: The Innovative Contributions of Jian-Shen Qi

Introduction

Jian-Shen Qi is a notable inventor based in Chalfont, PA, who has made significant contributions to the field of biochemistry. His work primarily focuses on the triglyceride synthesis pathway, which is crucial for understanding metabolic processes and developing therapeutic interventions.

Latest Patents

Jian-Shen Qi holds a patent for a method titled "Cell based screening assays for the triglyceride synthesis pathway." This innovative method involves identifying compounds that modulate the activity of acyl-coA: diacylglycerol acyltransferase. The process includes contacting stable isotope labeled fatty acids with cells, extracting the cells with isopropyl alcohol, and determining the levels of stable isotope labeled triglycerides. A change in these levels indicates that the compound affects DGAT activity, showcasing a novel approach to drug discovery.

Career Highlights

Throughout his career, Jian-Shen Qi has worked with prominent organizations such as Janssen Research & Development, LLC and Janssen Pharmaceutica NV. His experience in these companies has allowed him to contribute to various research projects and advancements in pharmaceutical sciences.

Collaborations

Jian-Shen Qi has collaborated with esteemed colleagues, including Wensheng Lang and Margery Connelly. These partnerships have fostered a collaborative environment that enhances research outcomes and innovation.

Conclusion

Jian-Shen Qi's contributions to the field of biochemistry, particularly through his patent on triglyceride synthesis, highlight his role as an influential inventor. His work continues to impact the scientific community and advance our understanding of metabolic pathways.