The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2015
Filed:
Jan. 07, 2010
Jian-shen Qi, Chalfont, PA (US);
Wensheng Lang, Lower Gwynedd, PA (US);
Margery A. Connelly, Lansdale, PA (US);
Jian-Shen Qi, Chalfont, PA (US);
Wensheng Lang, Lower Gwynedd, PA (US);
Margery A. Connelly, Lansdale, PA (US);
Janssen Research & Development, LLC, Raritan, NJ (US);
Abstract
A method for identifying a compound which modulates the activity of acyl-coA: diacylglycerol acyltransferase comprises the steps of contacting a stable isotope labeled fatty acid with cells in either presence or absence of the compound, extracting the cells with isopropyl alcohol, and determining the level of a stable isotope labeled triglyceride in the presence or absence of the compound; wherein a change in the level of the stable isotope labeled triglyceride indicates that the compound modulates the DGAT activity.