Company Filing History:
9 out of 1,935 
1 out of 896 
Years Active: 2010-2022
Title: The Innovative Contributions of Jia-Wang Wang
Introduction
Jia-Wang Wang is a prominent inventor based in Tampa, FL, known for his significant contributions to the field of gene editing and immunology. With a total of 9 patents, he has made remarkable strides in developing innovative techniques that enhance our understanding and treatment of various diseases.
Latest Patents
Wang's latest patents include an "Efficient CRISPR/HDR-mediated knock-in system and method of use." This patent focuses on the CRISPR gene editing technique, which utilizes the non-homologous end-joining (NHEJ) repair pathway to generate gene knockouts of varying sizes. By combining the homology-directed-repair (HDR) pathway with CRISPR cleavage, Wang has demonstrated that precise genome editing can be achieved. His research indicates that CRISPR/HDR without NHEJ inhibitors can result in highly efficient gene knock-ins, even for large DNA fragments. Another significant patent is related to "Inflammatory disease diagnosis and methods of treatment using down-regulators of lipopolysaccharide-responsive beige-like anchor." This work highlights the potential of targeting LRBA, a master regulator of multiple genes important for inflammation, to treat inflammatory diseases effectively.
Career Highlights
Wang has worked with esteemed institutions such as the University of South Florida and the United States Government as represented by the Department of Veterans Affairs. His research has not only advanced scientific knowledge but has also contributed to practical applications in medical treatments.
Collaborations
Throughout his career, Wang has collaborated with notable colleagues, including Richard F Lockey and Shyam S Mohapatra. These partnerships have fostered a collaborative environment that enhances the impact of his research.
Conclusion
Jia-Wang Wang's innovative work in gene editing and immunology has positioned him as a leading inventor in his field. His contributions continue to pave the way for advancements in medical science and treatment methodologies.