The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2015
Filed:
Feb. 20, 2013
Applicant:
University of South Florida, Tampa, FL (US);
Inventors:
Shyam S. Mohapatra, Lutz, FL (US);
Jia-Wang Wang, Tampa, FL (US);
Assignee:
UNIVERSITY OF SOUTH FLORIDA, Tampa, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7105 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7105 (2013.01); C12Q 1/6809 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/178 (2013.01);
Abstract
MicroRNAs are shown to be up- and/or down-regulated in inflammation and immune cells using a mouse model of asthma and regulatory T cells as source of RNA, respectively. Modulating the expression of these microRNAs can be effective in redirecting inflammation and immunity and hence, can be beneficial as biomarkers or as therapeutic agents against diverse human immunologic and inflammatory diseases.