Jia-Rong Chen

Title: Innovations of Jia-Rong Chen in Tumor Radiation Probes

Introduction

Jia-Rong Chen is a notable inventor based in Miaoli County, Taiwan. He has made significant contributions to the field of nuclear medicine, particularly in the development of tumor radiation probes. His innovative work has the potential to enhance the accuracy of tumor detection and treatment.

Latest Patents

Jia-Rong Chen holds a patent for a tumor radiation probe utilizing an iodine-123 marker thymidine (FLT) analogue, referred to as [I]-IaraU. This invention employs commercially available uridine as the raw material for synthesizing the precursor. The radioactive iodine-123 is marked on an alkaline group of uridine, distinguishing it from the [F]-FLT marking on a glycosyl group. The marking procedures involve mixing the marker precursor with Na [I] solution, acetic acid, and hydrogen peroxide solution, along with chloroform and sodium hydroxide. The sonication time is increased from 1 minute to 10 minutes, resulting in [I]-IaraU achieving a radiological chemical purity of over 98% and a radiological specific activity of no less than 0.196 GBq/umole. The yield can increase from 8% to 40%, making it suitable for biological experiments while reducing production costs.

Career Highlights

Jia-Rong Chen is affiliated with the Institute of Nuclear Energy Research under the Atomic Energy Council. His work at this institution has been pivotal in advancing research in nuclear medicine and developing innovative solutions for tumor detection.

Collaborations

Jia-Rong Chen has collaborated with notable colleagues, including Jenn-Tzong Chen and Ho-Lien Huang. Their combined expertise has contributed to the success of various projects within the field.

Conclusion

Jia-Rong Chen's contributions to the development of tumor radiation probes represent a significant advancement in medical technology. His innovative approach and dedication to research continue to impact the field positively.