Company Filing History:
Years Active: 2017-2025
Title: The Innovative Contributions of Ji Qiu
Introduction
Ji Qiu is a prominent inventor based in Chandler, AZ, known for his significant contributions to the field of medical research. With a total of seven patents to his name, he has made remarkable strides in understanding and diagnosing various medical conditions, particularly rheumatoid arthritis and breast cancer.
Latest Patents
Ji Qiu's latest patents focus on the identification and medical applications of anti-citrullinated-protein antibodies in rheumatoid arthritis. His work includes compositions and methods for detecting anti-citrullinated protein antibodies (ACPAs) in patients with rheumatoid arthritis (RA). In his research, patient samples known or suspected of containing ACPAs were probed against citrullinated proteins. He investigated antibody responses to 190 citrullinated proteins in 20 RA patients, revealing unique antibody reactivity patterns in both clinical anti-cyclic citrullinated peptide assay positive (CCP+) and negative (CCP−) RA patients. Notably, he discovered and validated six novel antibody/antigen complexes against specific citrullinated antigens, including Myelin Basic Protein (MBP) and insulin-like growth factor I (IGF1). His research also identified immune-dominant epitopes for citrullinated MBP, with the identified biomarkers demonstrating high specificity, particularly MBP.
Additionally, Ji Qiu has developed plasma autoantibody biomarkers for basal-like breast cancer. His research indicates that cancer patients produce antibodies to tumor-derived proteins, which can serve as potential biomarkers for early detection. He identified twenty-eight antigens as potential biomarkers for early detection of basal-like breast cancer and developed a 13-AAb classifier that differentiates patients with basal-like breast cancer from healthy controls with 33% sensitivity at 98% specificity.
Career Highlights
Throughout his career, Ji Qiu has worked with esteemed institutions such as Arizona State University and the University of Illinois. His innovative research has significantly advanced the understanding of autoimmune diseases and cancer diagnostics.
Collaborations
Ji Qiu has collaborated with notable professionals in his field, including Joshua LaBaer and Jie Wang. Their combined expertise has contributed to the success of his research endeavors.
Conclusion
Ji Qiu's innovative work in the medical field has led to significant advancements in the diagnosis and understanding of rheumatoid arthritis and breast cancer. His contributions continue to impact the scientific community
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