The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2024

Filed:

Sep. 08, 2022
Applicants:

Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US);

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

Inventors:

Joshua LaBaer, Chandler, AZ (US);

Jie Wang, Glendale, AZ (US);

Ji Qiu, Chandler, AZ (US);

Garrick Wallstrom, Mesa, AZ (US);

Karen Anderson, Scottsdale, AZ (US);

Jin Park, Phoenix, AZ (US);

Jonine Figueroa, Edinburgh, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); C07K 16/30 (2006.01); C12Q 1/6886 (2018.01); G01N 33/564 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57415 (2013.01); C07K 16/3015 (2013.01); C12Q 1/6886 (2013.01); G01N 33/564 (2013.01); C12N 15/11 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Cancer patients make antibodies to tumor-derived proteins that are potential biomarkers for early detection. Twenty-eight antigens have been identified as potential biomarkers for the early detection of basal-like breast cancer (Tables 1, 2). Also, a 13-AAb classifier has been developed that differentiate patients with BLBC from healthy controls with 33% sensitivity at 98% specificity (Table 3).


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