Ji Hye Yoon

Title: Ji Hye Yoon: Innovator in Cytokine Trimer Domain Technology

Introduction

Ji Hye Yoon is a prominent inventor based in Daejeon, South Korea. He has made significant contributions to the field of biotechnology, particularly in the development of novel fusion proteins. His work focuses on enhancing the binding capabilities of antibodies, which has important implications for pharmaceutical applications.

Latest Patents

Ji Hye Yoon holds a patent for a fusion protein comprising an antigen binding domain and a cytokine trimer domain. This invention relates to a cytokine trimer domain where a first monomer and a second monomer are linked by a linker, and a third monomer is coupled by a knob-into-hole mechanism. The novel fusion protein, known as a receptor-antibody conjugated engager (RACE), is created by replacing the constant region of an antibody with the cytokine trimer domain. RACE exhibits superior binding ability to the target receptor compared to the parent antibody, as well as excellent simultaneous binding ability to both the antigen and the target receptor. This innovation can be effectively utilized as a bispecific pharmaceutical composition.

Career Highlights

Ji Hye Yoon is currently employed at Ctcells, Inc., where he continues to advance his research in the field of immunology and biotechnology. His work has garnered attention for its potential to improve therapeutic strategies in treating various diseases.

Collaborations

Some of his notable coworkers include Kka Bi Son and Jeong Hyeon Bak, who contribute to the innovative environment at Ctcells, Inc. Their collaborative efforts enhance the research and development of cutting-edge biopharmaceuticals.

Conclusion

Ji Hye Yoon's contributions to the field of biotechnology, particularly through his patented innovations, highlight his role as a key inventor in advancing medical science. His work promises to have a lasting impact on the development of effective therapeutic solutions.