Company Filing History:
Years Active: 2005
Title: The Innovative Contributions of Jesus Ontoria
Introduction
Jesus Ontoria is a notable inventor based in Barcelona, Spain. She has made significant contributions to the field of molecular biology, particularly in the development of peptide inhibitors for the hepatitis C virus. Her work has the potential to impact the treatment of this viral infection, showcasing her innovative spirit and dedication to scientific advancement.
Latest Patents
Jesus Ontoria holds a patent for "Peptide inhibitors of hepatitis C virus NS3 protease." This patent describes fluorinated oligopeptides, especially those containing 4,4-difluoro-2-amino butyric acid at the C terminus, which may serve as effective inhibitors of the hepatitis C virus NS3 protease. The invention includes examples of hexapeptides optimized for binding in the S1 specificity pocket of the enzyme, displaying inhibitory concentrations at the sub-micromolar level. Additionally, embodiments of tripeptides with a keto-acid group at the C-terminus are also identified as potent inhibitors of NS3 protease.
Career Highlights
Jesus Ontoria is affiliated with the Istituto di Ricerche di Biologia Molecolare P. Angeletti Spa, where she continues her research and development efforts. Her work in this esteemed institution has allowed her to explore innovative solutions to complex biological problems.
Collaborations
Throughout her career, Jesus has collaborated with notable colleagues, including Victor Matassa and Frank Narjes. These partnerships have fostered a collaborative environment that enhances the research and development of new therapeutic approaches.
Conclusion
Jesus Ontoria's contributions to the field of molecular biology, particularly through her patent on peptide inhibitors for hepatitis C, highlight her role as an innovative inventor. Her work not only advances scientific knowledge but also holds promise for improving treatment options for patients.