Jessi Marie Wildeson

Title: Jessi Marie Wildeson: Innovator in Protein Kinase Inhibitor Assays

Introduction

Jessi Marie Wildeson is a notable inventor based in Thomaston, CT (US). She has made significant contributions to the field of biochemistry, particularly in the development of innovative screening assays for protein kinase inhibitors. With a total of 2 patents, her work is paving the way for advancements in drug discovery and therapeutic applications.

Latest Patents

Wildeson's latest patents focus on fluorescent probes for use in protein kinase inhibitor binding assays. The first patent provides methods relating to a screening assay format that can be applied to a broad range of protein kinase gene family members. This assay utilizes a series of labeled, active site probes that can be displaced by an inhibitor agent. The equilibrium constant (K) for the inhibitor compound is derived based on the K of the probe for the kinase and the dose response of the inhibitor agent. Additionally, the invention includes active site probes suitable for use with the screening method. The second patent mirrors the first, emphasizing the novel screening assay format and its applicability to the protein kinase gene family.

Career Highlights

Jessi Marie Wildeson is currently employed at Boehringer Ingelheim Pharmaceuticals, Inc., where she continues to innovate in the field of biochemistry. Her work is instrumental in enhancing the understanding of protein interactions and the development of new therapeutic agents.

Collaborations

Some of her notable coworkers include Scott E. Jakes and Martha Priscilla Brown, who contribute to the collaborative environment that fosters innovation at Boehringer Ingelheim.

Conclusion

Jessi Marie Wildeson is a pioneering inventor whose work in protein kinase inhibitor assays is making a significant impact in the field of drug discovery. Her contributions are essential for advancing therapeutic strategies and improving patient outcomes.