The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2006
Filed:
Sep. 30, 2004
Anthony S. Prokopowicz, Iii, Stormville, NY (US);
Martha Priscilla Brown, Southbury, CT (US);
Jessi Marie Wildeson, Thomaston, CT (US);
Scott Jakes, Southbury, CT (US);
Mark E. Labadia, Brookfield, CT (US);
Anthony S. Prokopowicz, III, Stormville, NY (US);
Martha Priscilla Brown, Southbury, CT (US);
Jessi Marie Wildeson, Thomaston, CT (US);
Scott Jakes, Southbury, CT (US);
Mark E. Labadia, Brookfield, CT (US);
Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT (US);
Abstract
The invention provides methods relating to a novel screening assay format that can be applied to broad members of the protein kinase gene family. The assay uses a series of labeled, active site probes described herein that can be displaced by an inhibitor agent. The Kfor the inhibitor compound is derived based on the Kof the probe for the kinase and the dose response of the inhibitor agent. The invention also provides active site probes suitable for use with the screening method.