This inventor holds 4 USPTO granted patents. Top assignee: Sri International. Active years: 1992-1993.
Company Filing History:
Years Active: 1992-1993
Title: Jerome B Lazar: Innovator in Protein Purification and Antimetastatic Peptides
Introduction
Jerome B Lazar is a notable inventor based in Sunnyvale, CA (US). He has made significant contributions to the field of biotechnology, particularly in the purification of proteins and the development of antimetastatic peptides. With a total of 4 patents to his name, Lazar's work has had a meaningful impact on medical and scientific research.
Latest Patents
One of Lazar's latest patents is titled "Purification of proteins employing CTAP-III fusions." This invention provides a process for recovering heterologous proteins from CTAP-III fusion proteins. The process involves expressing a fusion protein with specific amino acid sequences and a selectable site that can be cleaved to yield distinct polypeptide fragments. The first fragment is homologous to CTAP-III, and the two fragments possess different pI values. The fusion protein is cleaved, and the fragments are separated using ion exchange chromatography.
Another significant patent is "Antimetastatic peptides with laminin activity." This invention involves the production of human laminin B.sub.1 peptides, which exhibit substantial amino acid sequence similarity to a specific region in the human sequence. These novel peptides have been found to possess enhanced antimetastatic activity, showcasing their potential in cancer treatment.
Career Highlights
Jerome B Lazar is associated with SRI International, a renowned research institution known for its innovative contributions to various fields. His work at SRI has allowed him to explore and develop groundbreaking technologies that address critical challenges in biotechnology.
Collaborations
Lazar has collaborated with esteemed colleagues, including Paul H Johnson and Richard C Winant. These collaborations have fostered a productive environment for innovation and research, leading to advancements in their respective fields.
Conclusion
Jerome B Lazar's contributions to protein purification and antimetastatic peptides highlight his role as a significant inventor in biotechnology. His patents reflect a commitment to advancing scientific knowledge and improving medical treatments.