Company Filing History:
Years Active: 2013
Title: Jens Hennecke: Innovator in Polypeptide Technology
Introduction
Jens Hennecke is a notable inventor based in Germany, recognized for his contributions to the field of polypeptide technology. His innovative work focuses on enhancing the expression of polypeptides, which has significant implications in various biotechnological applications.
Latest Patents
Jens Hennecke holds a patent for "Expression-Enhanced Polypeptides." This composite polypeptide comprises a desired polypeptide and an expression enhancing domain (EED). The EED includes first and second cysteine amino acid residues, Cys1 and Cys2, respectively. Cys1 is located closer to the N-terminus of the composite polypeptide molecule than Cys2. These cysteine residues are separated by a peptide linker that is free of cysteine and proline, allowing for the formation of an intramolecular disulfide bond. The linker is designed to have a flexible conformation that is essentially free of secondary polypeptide structure in aqueous solution, with at least one of the cysteine residues derivatized with a derivatization moiety.
Career Highlights
Jens Hennecke is currently employed at Amgen Research GmbH, where he continues to advance his research in polypeptide technology. His work has contributed to the understanding and development of expression-enhancing techniques that are vital for biopharmaceutical production.
Collaborations
Throughout his career, Jens has collaborated with several esteemed colleagues, including Patrick Hoffmann and Silke Mittelstrass. These collaborations have fostered a productive environment for innovation and research in the field.
Conclusion
Jens Hennecke is a prominent figure in the realm of polypeptide technology, with a focus on enhancing expression through innovative methods. His contributions are paving the way for advancements in biotechnology and biopharmaceuticals.