This inventor holds 2 USPTO granted patents. Top assignee: University of Colorado. Active years: 2007-2008.
Company Filing History:
Years Active: 2007-2008
Title: The Innovations of Jeffrey W. Karpen
Introduction
Jeffrey W. Karpen is a notable inventor based in Portland, OR (US). He has made significant contributions to the field of biochemistry, particularly in the development of modified cyclic nucleotide gated ion channels. With a total of 2 patents, his work has implications for various scientific applications.
Latest Patents
Karpen's latest patents include innovations in modified cyclic nucleotide gated (CNG) channels. The first patent focuses on providing modified CNG channels that exhibit increased sensitivity and specificity for cAMP, compared to wild-type CNG channels. Additionally, regulation by Ca-calmodulin has been removed in these modified channels. The invention also includes convenient optical methods for detecting changes in cAMP, leveraging the permeability of the channel. Furthermore, electrophysiological methods are provided to enhance the functionality of these channels. His second patent mirrors the first, emphasizing the same advancements in modified CNG channels and their applications.
Career Highlights
Karpen is affiliated with the University of Colorado, where he continues to advance research in his field. His work has garnered attention for its innovative approach to understanding ion channels and their role in cellular processes.
Collaborations
Throughout his career, Karpen has collaborated with esteemed colleagues, including Thomas C. Rich and Dermot M. F. Cooper. These partnerships have contributed to the depth and breadth of his research.
Conclusion
Jeffrey W. Karpen's contributions to the field of biochemistry through his patented innovations in cyclic nucleotide gated ion channels highlight his role as a leading inventor. His work continues to influence scientific research and applications in significant ways.