Dallas, TX, United States of America

Jef K DeBrabander


Average Co-Inventor Count = 2.7

ph-index = 1

Forward Citations = 3(Granted Patents)


Location History:

  • Dallas, TX (US) (2016)
  • Flower Mound, TX (US) (2018 - 2023)

Company Filing History:


Years Active: 2016-2023

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4 patents (USPTO):Explore Patents

Title: Jef K DeBrabander: Innovator in Cancer Therapeutics

Introduction

Jef K DeBrabander is a prominent inventor based in Dallas, TX (US). He has made significant contributions to the field of cancer therapeutics, holding a total of 4 patents. His work focuses on developing innovative compounds that target cancer cells while sparing normal cells.

Latest Patents

One of his latest patents involves benzamide or benzamine compounds that are useful as anticancer agents for the treatment of human cancers. This invention provides small molecule anti-cancer compounds that treat tumors responsive to cholesterol biosynthesis inhibition. The compounds selectively inhibit the cholesterol biosynthetic pathway in tumor-derived cancer cells, without affecting normally dividing cells. Another notable patent addresses therapeutics targeting truncated adenomatous polyposis coli (APC) proteins. This invention offers small molecule anti-cancer compounds that selectively target and inhibit the measurable biological activity of truncated APC proteins, along with pharmaceutical compositions that include these compounds and a pharmaceutically acceptable carrier.

Career Highlights

Jef K DeBrabander is affiliated with the University of Texas System, where he continues to advance research in cancer treatment. His innovative approaches have garnered attention in the scientific community, contributing to the development of effective cancer therapies.

Collaborations

He has collaborated with notable colleagues such as Luis F Parada and Jerry W Shay, enhancing the impact of his research through shared expertise and insights.

Conclusion

Jef K DeBrabander's work exemplifies the intersection of innovation and healthcare, particularly in the fight against cancer. His patents reflect a commitment to developing targeted therapies that could significantly improve patient outcomes.

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