Location History:
- Ithaca, NY (US) (2001 - 2006)
- Oakland, CA (US) (2001 - 2021)
Company Filing History:
12 out of 15,502 
3 out of 3,271 
2 out of 755 
Years Active: 2001-2021
Title: **Jean M J Frechet: Pioneering Innovations in Polyhydroxylated Polymers**
Introduction
Jean M J Frechet is an accomplished inventor based in Oakland, CA, recognized for his significant contributions to the field of polymer science. With a remarkable portfolio of 20 patents, Frechet has made substantial advancements, particularly in the development of modified polyhydroxylated materials. His work has paved the way for innovative applications in the biomedical sector, especially in drug delivery systems.
Latest Patents
Frechet's latest patents focus on acid-degradable and bioerodible modified polyhydroxylated materials. The patents describe compositions and methods for creating modified polyhydroxylated polymers, which involve reversibly modifying hydroxyl groups through an acid-catalyzed reaction with reagents such as acetals, aldehydes, vinyl ethers, and ketones. The resulting polymers are insoluble in water yet soluble in common organic solvents, enabling the preparation of acid-sensitive materials. Importantly, these materials can degrade in a pH-dependent manner, providing versatility in loading both hydrophobic and hydrophilic cargoes using single and double emulsion techniques. Due to their ease of preparation, processability, pH-sensitivity, and biocompatibility, these modified polymers hold great promise for a wide range of drug delivery applications.
Career Highlights
Frechet has had a distinguished career, holding positions at renowned institutions including the University of California and ExxonMobil Chemical Patents Inc. His research and patents have garnered attention and respect in the scientific community, solidifying his role as a leader in polymer innovation.
Collaborations
Throughout his career, Frechet has collaborated with notable professionals in the field, including Damian A Hajduk and Ezat Khoshdel. These collaborations have further enriched his research and contributed to the success of his patents.
Conclusion
Jean M J Frechet's work exemplifies the intersection of innovation and practical application in polymer chemistry. His patents on acid-degradable and bioerodible modified polyhydroxylated materials not only reflect his inventive spirit but also highlight the potential for significant advancements in drug delivery technologies. As Frechet continues to push the boundaries of polymer science, his contributions remain vital to the evolving landscape of biomedical applications.