The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7056901 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 06, 2006

Filed:

Mar. 28, 2003
Applicants:

Jean M. J. Frechet, Oakland, CA (US);

Niren Murthy, Berkeley, CA (US);

Inventors:

Jean M. J. Frechet, Oakland, CA (US);

Niren Murthy, Berkeley, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 37/715 (2006.01); A61K 39/00 (2006.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel microgels, microparticles and related polymeric materials capable of delivering bioactive materials to cells for use as vaccines or therapeutic agents. The materials are made using a crosslinker molecule that contains a linkage cleavable under mild acidic conditions. The crosslinker molecule is exemplified by a bisacryloyl acetal crosslinker. The new materials have the common characteristic of being able to degrade by acid hydrolysis under conditions commonly found within the endosomal or lysosomal compartments of cells thereby releasing their payload within the cell. The materials can also be used for the delivery of therapeutics to the acidic regions of tumors and sites of inflammation.


Find Patent Forward Citations

Frechet, Jean M. J.. (2006). Microgel particles for the delivery of bioactive materials (U.S. Patent No. 7056901). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7056901

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