Jean Heather Crinean

Title: Jean Heather Crinean: Innovator in Polysaccharide Production

Introduction

Jean Heather Crinean is a notable inventor based in Saint Charles, MO (US). She has made significant contributions to the field of polysaccharide production, holding 2 patents that showcase her innovative methods.

Latest Patents

One of her latest patents is titled "Method for controlling polysaccharide molecular weight using carbon dioxide." This invention provides improved methods for producing a solution containing high molecular weight isolated capsular polysaccharides with phosphodiester linkages between saccharide repeat units. The method involves supplying carbon dioxide to a fermentation culture of bacterial cells that produce capsular polysaccharide serotypes, including serotypes 6A, 6B, 19A, and 19F. The process includes adding bicarbonate ions, carbonate ions, or mixtures of both to the fermentation culture, as well as overlaying the culture with carbon dioxide.

Another patent focuses on producing high molecular weight isolated 19A capsular polysaccharides. In this method, a fermentation culture of bacterial cells is fermented for less than six hours before lysing the cells to harvest the capsular polysaccharides. Similar to her previous patent, this method also involves supplying carbon dioxide to the fermentation culture.

Career Highlights

Jean Heather Crinean is associated with Wyeth, a company known for its advancements in pharmaceuticals and biotechnology. Her work at Wyeth has allowed her to contribute to innovative solutions in the field of polysaccharides.

Conclusion

Jean Heather Crinean's contributions to polysaccharide production through her patents demonstrate her commitment to innovation in biotechnology. Her work continues to influence the industry and pave the way for future advancements.