Mantes La Ville, France

Jean-Baptiste Graux


Average Co-Inventor Count = 6.5

ph-index = 2

Forward Citations = 7(Granted Patents)


Company Filing History:


Years Active: 1991-1992

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2 patents (USPTO):Explore Patents

Title: Innovator Spotlight: Jean-Baptiste Graux

Introduction

Jean-Baptiste Graux, an esteemed inventor based in Mantes La Ville, France, has made notable contributions to the field of chemical innovations. With a total of two patents to his name, Graux's work reflects a commitment to advancing methodologies within the realm of organic chemistry.

Latest Patents

Graux's latest patents showcase his innovative approach to preparing complex chemical compounds. His first patent details a method where 2-aminothiophenol is reacted with methyl (-)-(2R,3S)-2,3-epoxy-3-(4-methoxyphenyl)propionate. The process includes the cyclization of the intermediate methyl (2S,3S)-3-[(2-aminophenyl)thio]-2-hydroxy-3-(4-methoxyphenyl)propionate in the presence of methanesulfonic acid, all conducted in a single vessel without isolating the intermediate product, utilizing chlorobenzene as a solvent.

The second patent similarly involves the reaction of 2-aminothiophenol, but with a slight variation, using (-)-(2R,3S)-2,3-epoxy-3-(4-methoxyphenyl)methylpropionate. Again, the intermediate (2S,3S)-3-[(2-aminophenyl)thio]-2-hydroxy-3-(4-methoxyphenyl)methylpropionate is cyclized under comparable conditions, emphasizing the efficiency of conducting reactions in a unified approach.

Career Highlights

Graux is associated with Synthelabo, a prominent player in the pharmaceutical field. In his tenure, he has demonstrated a remarkable ability to innovate within his domain, contributing valuable techniques that enhance the capabilities of chemical compounds used in various applications.

Collaborations

Throughout his career, Jean-Baptiste Graux has collaborated with notable colleagues such as Guy Rossey and Isaac Chekroun. These partnerships have fostered a rich exchange of ideas and expertise, further propelling advancements in their shared projects.

Conclusion

Jean-Baptiste Graux stands as a testament to the potential of innovation within the chemical sciences. His recent patents not only signify his inventiveness but also illustrate the collaborative spirit that drives progress in technology and methodologies. As he continues to work with Synthelabo, the future holds promise for further advancements stemming from his research and dedication to improving chemical processes.

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