The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 1991
Filed:
Sep. 14, 1989
Applicant:
Inventors:
Guy Rossey, Voisins-Le-Bretonneux, FR;
Isaac Chekroun, Epinay, FR;
Antonio Ugolini, Le Pecq, FR;
Alexander Wick, St. Nom La Breteche, FR;
Bernard Gerin, Mantes La Jolie, FR;
Andre Bourbon, Mantes La Jolie, FR;
Jean-Baptiste Graux, Mantes La Ville, FR;
Assignee:
Synthelabo, Paris, FR;
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
540491 ;
Abstract
2-Aminothiophenol is reacted with (-)-(2R,3S)-2,3-epoxy-3-(4-methoxyphenyl) methylpropionate, and the intermediate (2S,3S)-3-[(2-aminophenyl)thio]-2-hydroxy-3-(4-methoxyphenyl) methylpropionate is then cyclized in the presence of methane sulfonic acid, in the same container and without isolating said intermediate product, using chlorobenzene as a solvent.