Location History:
- Palo Alto, CA (US) (2018)
- Redwood City, CA (US) (2016 - 2023)
Company Filing History:
Years Active: 2016-2023
Title: Innovator Spotlight: Jason D. Buenrostro
Introduction
Jason D. Buenrostro, based in Redwood City, California, is a prominent inventor known for his groundbreaking contributions to the field of genomics. With a total of 13 patents to his name, Buenrostro is making significant strides in understanding and manipulating the genome.
Latest Patents
His latest innovations showcase advanced methodologies in genetic research. One of his notable patents is titled "Transposase-mediated imaging of the accessible genome," which describes methods for labeling and imaging accessible regions of the genome. This patent employs a bifunctional transposase complex or transposome to insert adaptors with various chemical tags at active regulatory DNA sites. These tags can facilitate a range of imaging techniques, including fluorescence imaging and electron microscopy, thus providing spatial insights on regulatory DNA positioning.
Another significant patent is "Transposition of native chromatin for personal epigenomics." This inventive method outlines the process for analyzing polynucleotides such as genomic DNA. It involves treating chromatin from a cell population with an insertional enzyme complex, sequencing the tagged fragments, and creating an epigenetic map of the genome. This patent not only enhances genomic comprehension but also provides tools for further epigenomic research through its accompanying kit.
Career Highlights
Jason D. Buenrostro is affiliated with Leland Stanford Junior University, where he continues to advance his research and development in genomics. His career reflects a dedication to enhancing the understanding of genetic structure and function, particularly in regulatory areas of the genome.
Collaborations
Throughout his career, Buenrostro has collaborated with influential peers, including William J. Greenleaf and Howard Y. Chang. Together, they contribute to the expanding knowledge base in genetic research and technology.
Conclusion
Jason D. Buenrostro is an innovative force in the field of genomics, with a suite of patents that push the boundaries of scientific understanding. His work not only contributes valuable insight into the genome's organization but also paves the way for future advancements in genetic research and applications.