Jason Crawford

Title: Jason Crawford: Innovator in Antibacterial Compounds

Introduction

Jason Crawford is a notable inventor based in Shelton, CT (US). He has made significant contributions to the field of antibacterial compounds, holding 2 patents that showcase his innovative approach to combating bacterial infections.

Latest Patents

Crawford's latest patents include "Anti-bacterial stilbene derivatives and methods of use." This patent presents novel antibacterial compounds of Formula I, which can be synthesized through enzymatic oxidative dimerization in the presence of a suitable organism and one or more metal salts. Remarkably, pathogenic bacteria exposed to these compounds do not develop resistance, even after prolonged exposure. Additionally, the patent outlines methods for treating bacterial infections and for killing or disinfecting bacteria. Another significant patent is "Heterologous production of leupeptin protease inhibitors and analogs thereof." This disclosure includes a construct comprising a leupeptin biosynthesis operon, which consists of the leupA, leupB, leupC, and leupD genes operably linked to a promoter. It also covers cells that contain this construct and methods for producing leupeptin peptide.

Career Highlights

Crawford is affiliated with Yale University, where he continues to advance his research and innovation in the field of antibacterial compounds. His work has the potential to significantly impact the treatment of bacterial infections.

Collaborations

Crawford collaborates with talented individuals such as Tyler Goddard and Hyun Bong Park, contributing to a dynamic research environment.

Conclusion

Jason Crawford's innovative work in antibacterial compounds positions him as a key figure in the fight against bacterial infections. His patents reflect a commitment to developing effective solutions that address critical health challenges.