The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2025
Filed:
Apr. 17, 2020
Applicant:
Yale University, New Haven, CT (US);
Inventors:
Jason Crawford, Shelton, CT (US);
Tyler Goddard, Cambridge, MA (US);
Hyun Bong Park, West Haven, CT (US);
Jaymin Patel, New Haven, CT (US);
Assignee:
Yale University, New Haven, CT (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 50/28 (2005.12); A01N 35/06 (2005.12); A01P 1/00 (2005.12); A61K 9/00 (2005.12); A61P 31/02 (2005.12);
U.S. Cl.
CPC ...
C07C 50/28 (2012.12); A01N 35/06 (2012.12); A01P 1/00 (2021.07); A61K 9/0014 (2012.12); A61P 31/02 (2017.12);
Abstract
Provided herein are novel antibacterial compounds of Formula I. The compounds can be made through enzymatic oxidative dimerization in the presence of a suitable organism and one or more metal salts. Pathogenic bacteria exposed to the compound of Formula I do not develop resistance to these compounds even after prolonged exposure. Also provided herein are methods of treating bacterial infections, and method of killing or disinfecting bacteria.