Location History:
- Palo Alto, CA (US) (2018 - 2019)
- South San Francisco, CA (US) (2016 - 2020)
Company Filing History:
Years Active: 2016-2020
Title: Innovations by Jason Casolari
Introduction
Jason Casolari is an accomplished inventor based in South San Francisco, California. He has made significant contributions to the field of biotechnology, particularly in the area of fatty acid production. With a total of six patents to his name, his work focuses on enhancing the profiles of fatty acids through innovative genetic engineering techniques.
Latest Patents
Among his latest patents, one notable invention is related to thioesterases and cells for the production of tailored oils. This invention features plant acyl-ACP thioesterase genes of the FatB class, which are instrumental in constructing recombinant host cells with altered fatty acid profiles. The microalgae cells that incorporate these new genes are capable of producing triglycerides with beneficial fatty acid profiles. Another significant patent involves ketoacyl ACP synthase genes and their applications. This invention pertains to beta-ketoacyl ACP synthase genes of the KASI/KASIV type, which can be included in nucleic acid constructs, vectors, or host cells. The expression of these gene products can modify the fatty acid profile of host cells, and when combined with a FATA or FATB thioesterase gene, they can create cells that produce increased amounts of C8-C16 fatty acids.
Career Highlights
Throughout his career, Jason has worked with prominent companies in the biotechnology sector, including Corbion Biotech, Inc. and Solazyme, Inc. His experience in these organizations has allowed him to develop and refine his innovative ideas, contributing to advancements in the production of tailored oils and fatty acids.
Collaborations
Jason has collaborated with notable professionals in his field, including George N Rudenko and Scott Franklin. These partnerships have facilitated the exchange of ideas and expertise, further enhancing the impact of his inventions.
Conclusion
Jason Casolari's work exemplifies the intersection of innovation and biotechnology. His patents reflect a commitment to advancing the production of tailored oils through genetic engineering. His contributions continue to influence the field and pave the way for future advancements.