The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 13, 2018

Filed:

Sep. 18, 2015
Applicant:

Corbion Biotech, Inc., South San Francisco, CA (US);

Inventors:

Jason Casolari, South San Francisco, CA (US);

George N. Rudenko, South San Francisco, CA (US);

Scott Franklin, South San Francisco, CA (US);

Xinhua Zhao, South San Francisco, CA (US);

Assignee:

CORBION BIOTECH, INC., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); C12N 15/52 (2006.01); C12N 15/00 (2006.01); C12N 1/12 (2006.01); C12P 7/64 (2006.01); C12N 9/24 (2006.01); C12N 15/82 (2006.01); C12N 9/04 (2006.01); C12P 7/44 (2006.01);
U.S. Cl.
CPC ...
C12P 7/6463 (2013.01); C12N 9/0006 (2013.01); C12N 9/16 (2013.01); C12N 9/2402 (2013.01); C12N 15/52 (2013.01); C12N 15/8247 (2013.01); C12P 7/44 (2013.01); C12Y 301/02014 (2013.01);
Abstract

Novel plant acyl-ACP thioesterase genes of the FatB and FatA classes and proteins encoded by these genes are disclosed. The genes are useful for constructing recombinant host cells having altered fatty acid profiles. Expression of the novel and/or mutated FATB and FATA genes is demonstrated in oleaginous microalga host cells. Furthermore, a method for producing an oil elevated in one or more of C12:0, C14:0, C16:0, C18:0 and/or C18:1 fatty acids includes transforming a cell with novel and/or mutated FATB and/or FATA genes, e.g., having an N-terminal deletion. The cells produce triglycerides with altered and useful fatty acid profiles.


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