This inventor holds 2 USPTO granted patents and 2 published patent applications. Top assignee: Wisconsin Alumni Research Foundation. Active years: 2021-2023.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Madison, WI (US) (2021)
- Burlingame, CA (US) (2023)
Company Filing History:
Years Active: 2021-2023
Title: Innovations by Jared Matthew Carlson-Stevermer
Introduction
Jared Matthew Carlson-Stevermer is an accomplished inventor based in Madison, WI (US). He has made significant contributions to the field of genetic research, particularly in the area of gene correction for autosomal recessive disorders. With a total of 2 patents, his work is paving the way for advancements in medical treatments.
Latest Patents
His latest patents include groundbreaking research on gene correction of Pompe disease and other autosomal recessive disorders via RNA-guided nucleases. This patent describes guide RNAs and modified guide RNAs that are suitable for biallelic correction of Pompe disease. The methods outlined involve modifying a target gene in a patient or patient-derived cell, specifically for those with compound heterozygous mutations. The process includes delivering a first modified guide RNA, a second modified guide RNA, a Cas9 polypeptide, and biotinylated donor polynucleotides to correct diseased alleles effectively.
Another notable patent focuses on modified guide RNAs, CRISPR-ribonucleoprotein complexes, and their methods of use. This patent details a single guide RNA that includes a protospacer sequence, complementary strands for binding with the Cas9 polypeptide, and an aptamer that binds a biotin-binding molecule. The RNP complex described in this patent is essential for modifying target genes in cells using these innovative guide RNAs.
Career Highlights
Jared is associated with the Wisconsin Alumni Research Foundation, where he continues to develop his research and innovations. His work is instrumental in advancing genetic therapies that could potentially change the lives of individuals suffering from genetic disorders.
Collaborations
He collaborates with notable colleagues such as Krishanu Saha and Lucille Katherine Kohlenberg, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Jared Matthew Carlson-Stevermer's contributions to genetic research and his innovative patents are significant steps forward in the field of medicine. His work exemplifies the potential of genetic engineering to address complex health issues.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile